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Related Experiment Videos

Osteopathy due to methotrexate.

A Koller, H Fill, R Kurz

    Osterreichische Zeitschrift Fur Onkologie. Austrian Journal of Oncology
    |September 13, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Long-term methotrexate therapy in children with acute lymphoblastic leukemia (ALL) can cause severe osteoporosis and fractures. An unknown additional factor may contribute to this methotrexate side effect.

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    Area of Science:

    • Pediatric Oncology
    • Pharmacology
    • Metabolic Bone Disease

    Background:

    • Acute lymphoblastic leukemia (ALL) is a common childhood cancer.
    • Methotrexate is a cornerstone chemotherapy agent used in ALL treatment.
    • Long-term methotrexate use can have significant side effects.