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Xenon-enhanced computed tomography quantifies normal maxillary sinus ventilation
D Leopold1, S J Zinreich, B A Simon
1Department of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198-1225, USA.
Objective:
The purpose of this study was to determine the applicability, safety, and normal parameters of a xenon-enhanced CT technique to quantify maxillary sinus ventilation.
Patients And Methods:
Nine healthy subjects inhaled a xenon-oxygen-air mixture through their noses while repeated CT scans were performed through the same section of their sinuses. Images were obtained every 1 to 3 minutes and analyzed to measure the density of the gas in the maxillary sinus as a function of time.
Results:
Individual nasal cavity time constants ranged from 0.5 to 18 minutes. Studies performed after decongestion showed poorer sinus ventilation.
Conclusions:
The xenon-CT washin/washout technique is safe, effective, and gives representative data.