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Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
DNA fragmentation in the CA2 sector of gerbil hippocampus following transient forebrain ischemia
1Department of Neurosurgery, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu, Japan. tiwai@cc.gifu-u.ac.jp
Brain Research
|March 4, 2000
Abstract:
It has been reported that following transient forebrain ischemia in the gerbil, "delayed neuronal death" and "reactive change" occur in hippocampal CA1 and CA2 sectors, respectively. In the present study, using the gerbil transient forebrain ischemia model, we examined brain sections after various recirculation periods and demonstrated, employing the in situ nick-end labeling (TUNEL) method, a nuclear DNA fragmentation in the damaged CA2 neurons.
