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Published on: June 16, 2013
Advances in non-invasive imaging of intracranial vascular disease
1Lysholm Radiological Department, National Hospital for Neurology and Neurosurgery, London, UK. r.jager@ion.ucl.ac.uk
Insights
Magnetic resonance angiography (MRA) and CT angiography (CTA) offer non-invasive methods for imaging intracranial vascular disease, reducing risks associated with traditional catheter angiography.
Area of Science:
- Neuroradiology
- Medical Imaging
- Vascular Diagnostics
Background:
- Intra-arterial catheter angiography was the standard for diagnosing intracranial vascular disease.
- This invasive method carries a 1-3% risk of neurological complications and requires hospitalization.
Purpose of the Study:
- To explain the technical principles of Magnetic Resonance Angiography (MRA) and CT Angiography (CTA).
- To provide an overview of the current clinical applications of MRA and CTA in neuroradiology.
Main Methods:
- Review of non-invasive imaging techniques: Magnetic Resonance Angiography (MRA) and CT Angiography (CTA).
- Focus on the underlying technical principles and diagnostic capabilities.
Main Results:
- MRA and CTA have emerged as significant non-invasive alternatives to catheter angiography.
- These advanced imaging modalities offer substantial impact in neuroradiological investigations.
Conclusions:
- MRA and CTA represent a paradigm shift in the investigation of intracranial vascular disease.
- These non-invasive techniques provide valuable diagnostic information with reduced patient risk compared to conventional angiography.
Abstract:
Intra-arterial catheter angiography has, in the past, been the mainstay for the investigation of intracranial vascular disease. It is, however, invasive, usually requires in-patients admission, and is associated with a rate of neurological complications between 1% and 3%. In recent years, magnetic resonance angiography (MRA) and CT angiography (CTA) have emerged as non-invasive alternatives for imaging blood vessels and have made a significant impact on neuroradiological investigations. It is the purpose of this article to explain the basic technical principles of these two methods and to give an overview of their current clinical applications.

