Pathogenesis and treatment of HIV-1 infection: recent developments (Y2K update)
Related Experiment Video
Updated: Oct 17, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
S L Dewhurst1, R L da Cruz, L Whetter
1Department of Microbiology and Immunology, 2 Cancer Center, University of Rochester Medical Center, Rochester NY 14642, USA. stephen_dewhurst@urmc.rochester.edu
Abstract:
Human immunodeficiency virus type 1 (HIV-1) is the etiologic agent of acquired immunodeficiency syndrome (AIDS). The pathogenesis of HIV-1-induced disease is complex and characterized by the interplay of both viral and host factors, which together determine the outcome of infection. An improved understanding of the pathogenic mechanisms of AIDS, combined with recent insights into the dynamics of viral infection may provide powerful new opportunities for therapeutic intervention against this virus.
Related Concept Videos
Retrovirus Life Cycles
Inhibitors of Virion Maturation and Assembly
Genital Herpes
Inhibitors of Viral Protein Synthesis
Antiviral Nucleoside Inhibitors
Retroviruses

