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Acute rheumatic fever in Konya, Turkey
S Karaaslan1, B Oran, I Reisli
1Department of Pediatrics, Faculty of Medicine, Selçuk University, Konya, Turkey.
Summary
Acute rheumatic fever (ARF) remains a significant concern, with arthritis and carditis being the most common symptoms. Prompt penicillin treatment is crucial for preventing ARF recurrences.
Area of Science:
- Pediatric Cardiology
- Rheumatology
- Infectious Diseases
Background:
- Acute rheumatic fever (ARF) poses a significant health challenge, particularly in pediatric populations.
- Retrospective analysis of ARF cases admitted to Selçuk University Faculty of Medicine between 1993 and 1998.
Purpose of the Study:
- To determine the clinical profile of ARF in pediatric patients.
- To compare ARF manifestations and outcomes with international data.
- To assess the prevalence and impact of ARF in the Konya region.
Main Methods:
- Retrospective chart review of 274 pediatric ARF patients.
- Clinical examinations, chest X-rays, ECGs, and echocardiography.
- Laboratory investigations including throat culture, ASO, CRP, and ESR.
Main Results:
- ARF occurrence rate of 3.4% among admitted patients.
- Arthritis (81.4%), carditis (60.9%), and chorea (17.9%) were the most frequent manifestations.
- Mitral valve involvement was predominant (95.8%), with 21% of mitral regurgitation cases resolving.
Conclusions:
- ARF continues to be a substantial public health issue in Konya.
- Effective prevention of ARF recurrences is achievable with a 3-week benzathine penicillin G regimen.