Related Experiment Videos
Developmental defects and chromosomal aberrations in spontaneous abortions and stillbirths
J Vojtassák1, J Malová, L Demjenová
1Institute of Medical Biology, School of Medicine, Comenius University, Bratislava, Slovakia. vojtassak@medik.fmed.uniba.sk
General Physiology and Biophysics
|March 7, 2000
Abstract:
The authors analysed 1488 cases of spontaneous abortions and stillbirths in Bratislava. They focused on the course of human embryogenesis and the chromosomal constitution. A high mean frequency rate of both developmental defects (14.4%) and chromosomal aberrations (33.6%) was revealed and both were found to be in close relation with the length of gestation. The most severe developmental defects occurred mostly in early stages of human embryogenesis, i.e. in the 1st trimester of gestation.