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Related Experiment Videos

Awareness during anaesthesia: a prospective case study.

R H Sandin1, G Enlund, P Samuelsson

  • 1Department of Anaesthesia and Intensive Care, Länssjukhuset, Kalmar, Sweden. rolfs@ltkalmar.se

Lancet (London, England)
|March 7, 2000
PubMed
Summary
This summary is machine-generated.

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General anesthesia awareness affects 0.18% of patients, with most cases detected through later interviews. Current protective measures are insufficient, suggesting a need for neurophysiological monitoring to prevent patient suffering.

Area of Science:

  • Anesthesiology
  • Neuroscience

Background:

  • General anesthesia does not guarantee unconsciousness during surgery.
  • Knowledge on protective measures and patient responses to awareness is limited.

Purpose of the Study:

  • To assess conscious awareness during general anesthesia.
  • To evaluate the effectiveness of current protective measures.

Main Methods:

  • Prospective case study involving 11,785 patients undergoing general anesthesia.
  • Patients were interviewed for awareness at three time points: post-anesthesia care unit, 1-3 days, and 7-14 days post-operation.

Main Results:

  • 18 cases of awareness and 1 case of inadvertent muscle blockade were identified.
  • Incidence of awareness was 0.18% with neuromuscular blocking drugs and 0.10% without.

Related Experiment Videos

  • Delayed interviews significantly increased awareness detection; 17/18 cases identified at final interview.
  • Non-paralyzed patients had fewer adverse psychological outcomes compared to those under muscle relaxants.

    • Conclusions:

    • Conventional measures are insufficient to prevent anesthesia awareness.
    • Neurophysiological monitoring of cerebral activity is suggested, but its sensitivity is unknown.
    • At least 861 patients require monitoring to prevent one case of suffering from awareness during relaxant anesthesia.