Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

TANAX(T-61): an overview.

M Giorgi1, S Bertini

  • 1Section of Pharmacology and Toxicology, Department of Veterinary Clinics, University of Pisa, V.le delle Piagge 2, Pisa, 56124, Italy.

Pharmacological Research
|March 8, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disposition kinetics and tissue residues of Lincomycin following intravenous, intramuscular and single and multiple oral dosing in domestic geese (<i>Anser anser domesticus</i>).

British poultry science·2025
Same author

N-Acetyl-leucine in progressive CACNA1A ataxia: A case series.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2025
Same author

Pharmacokinetics of tolfenamic acid in ducks (<i>Anas platyrhynchos domestica</i>) after different administration routes.

British poultry science·2024
Same author

Imipramine in dogs: A pharmacokinetic study following oral administration under fasted and fed conditions.

Veterinary journal (London, England : 1997)·2024
Same author

Search for Leptonic Decays of Dark Photons at NA62.

Physical review letters·2024
Same author

The anatomy of the pelvic plexus in female cadavers: implications for retroperitoneal nerve-sparing surgery.

Facts, views & vision in ObGyn·2024
Same journal

GLP-1 Receptor Agonist Therapy in Children and Adolescents with Obesity: A Network Meta-Analysis of Differential Cardiometabolic Efficacy and Safety Profiles.

Pharmacological research·2026
Same journal

Sinomenine regulates the AKT/FOXO3/GLUL pathway to inhibit pulmonary fibroblast-to-myofibroblast transition via α7nAChR against rheumatoid arthritis associated interstitial lung disease.

Pharmacological research·2026
Same journal

Ketohexokinase: A central mediator of fructose-associated pathogenesis and promising therapeutic target.

Pharmacological research·2026
Same journal

GLP-1-based combination strategies for weight loss: Multi-target agents and combination therapies.

Pharmacological research·2026
Same journal

Cajaninstilbene acid in macrophage immunometabolism and angiogenesis: Mechanisms and therapeutic potential.

Pharmacological research·2026
Same journal

From Mechanisms to Therapy: Targeting the Gut-Brain Axis in Chronic Gastrointestinal Pain.

Pharmacological research·2026
See all related articles

Tanax (T-61), a euthanasia solution containing embutramide, mebenzonium iodide, and tetracaine hydrochloride, is reviewed for its use in animals and humans. The study also covers its toxic effects and detection methods.

Area of Science:

  • Veterinary Pharmacology
  • Toxicology
  • Forensic Science

Background:

  • Tanax (T-61) is a multi-component solution utilized for animal euthanasia.
  • Its applications extend to veterinary medicine, laboratory animal science, and unfortunately, non-medical uses.
  • The formulation includes embutramide, mebenzonium iodide, and tetracaine hydrochloride, dissolved in N,N-dimethylformamide.

Purpose of the Study:

  • To provide a comprehensive overview of Tanax (T-61) usage.
  • To detail the toxicological profile of Tanax, including secondary effects from its solvent.
  • To describe analytical techniques for identifying Tanax in biological samples.

Main Methods:

  • Literature review on Tanax (T-61) applications and toxicology.
  • Analysis of case reports and scientific publications regarding Tanax intoxication.

Related Experiment Videos

  • Description of established analytical methodologies for forensic and clinical toxicology.

    • Main Results:

    • Tanax (T-61) is effective for euthanasia in animals but also implicated in animal abuse and human suicide attempts.
    • N,N-dimethylformamide, the solvent, can cause significant secondary toxic effects.
    • Various analytical methods, including chromatography and spectroscopy, are available for Tanax component detection.

    Conclusions:

    • Tanax (T-61) presents a complex toxicological profile requiring careful consideration in both veterinary and forensic contexts.
    • Understanding the solvent's contribution to toxicity is crucial for accurate assessment.
    • Reliable analytical methods are essential for confirming Tanax exposure.