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Anion modulation of calcium current voltage dependence and amplitude in salamander rods
1Department of Ophthalmology, University of Nebraska Medical Center, 985540 Nebraska Medical Center, Omaha, NE 68198-5540, USA. wbthores@unmc.edu
Biochimica Et Biophysica Acta
|March 8, 2000
Abstract:
Hofmeister anions were used to investigate the ability of Cl(-) replacement to produce inhibition and a hyperpolarizing activation shift in L-type Ca(2+) currents (I(Ca)) of rod photoreceptors. Inhibition of I(Ca) largely followed the Hofmeister sequence: Cl(-)=Br(-)