[Primary retroperitoneal seminoma--a rare germ cell neoplasm]

Area of Science:

• Oncology
• Urology

Background:

• Extragonadal germ cell tumors, particularly seminomas, are rare.
• Retroperitoneal masses can present with non-specific symptoms like abdominal pain.

Observation:

• A 44-year-old male presented with left-sided abdominal pain, a supraclavicular lymph node, and atrophic testes.
• Imaging revealed a large retroperitoneal mass.
• Biopsy confirmed seminoma, but primary testicular tumors were absent.

Findings:

• Diagnosis of extragonadal primary retroperitoneal seminoma was established.
• The patient responded favorably to cisplatin, bleomycin, and etoposide chemotherapy.
• Histological examination of testes is mandatory to differentiate from occult or burned-out primary testicular seminoma.

Implications:

• This case highlights the importance of considering extragonadal germ cell tumors.
• Definitive diagnosis requires thorough testicular evaluation.
• Chemotherapy regimens are effective for retroperitoneal seminomas.