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Serial intelligence test scores in pediatric moyamoya disease.

C Imaizumi1, T Imaizumi, M Osawa

  • 1Imaizumi Pediatric Clinic, Gunma, Maebashi-shi, Japan.

Neuropediatrics
|March 8, 2000
PubMed
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Intelligence in children with moyamoya disease declines after symptom onset. IQ scores decrease significantly within 5-10 years and stabilize thereafter, indicating a long-term impact.

Area of Science:

  • Neurology
  • Pediatrics
  • Neuropsychology

Background:

  • Moyamoya disease is a rare, progressive cerebrovascular disorder affecting children.
  • Understanding the long-term cognitive impact of moyamoya disease is crucial for patient management.

Purpose of the Study:

  • To evaluate the longitudinal changes in intelligence quotient (IQ) scores in children diagnosed with moyamoya disease.

Main Methods:

  • Serial IQ tests were administered to 38 pediatric patients with moyamoya disease.
  • IQ scores were analyzed across three time periods post-symptom onset: 0-5 years, 5-10 years, and >10 years.
  • Mean IQ scores were calculated for patients with multiple tests within each period.

Main Results:

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  • IQ scores were significantly lower in the 5-10 years (76.8 ± 23.1) and >10 years (73.9 ± 31.1) categories compared to the 0-5 years category (92.9 ± 22.7).
  • Five out of 10 patients tested multiple times in the 0-5 years category showed declining IQ scores.
  • No significant difference in IQ scores was observed between the 5-10 years and >10 years categories.

    • Conclusions:

    • Intelligence in pediatric moyamoya disease patients declines after symptom onset.
    • The decline in IQ appears to stabilize more than 10 years after the onset of symptoms.