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Evaluation of an antiseptic triple-lumen catheter in an intensive care unit
E M Hanley1, A Veeder, T Smith
1Department of Epidemiology, Albany Medical Center Hospital, New York 12208, USA.
Objective:
To evaluate a decrease in catheter-related bloodstream infection rate in patients with antiseptic triple-lumen catheters in an intensive care unit.
Data Sources:
Retrospective review of surveillance records, patient medical records, laboratory and microbiological reports, and antibiotic administration records.
Study Selection:
Patients admitted to the intensive care unit with triple-lumen catheters.
Data Extraction:
A subset of one entry per patient was extracted from 2 yrs of primary bloodstream infection surveillance data. Data collection included risk factors, laboratory and microbiological data, and insertion sites and dates of all intravascular catheters present during triple-lumen catheterization.
Data Synthesis:
The catheter-related bloodstream infection rate was 5.4 and 11.3 per 1000 catheter days in antiseptic and nonantiseptic triple-lumen catheter groups, respectively (p = .06). By multivariate analysis using a Cox Proportional Hazards Model, the antiseptic triple-lumen catheters were associated with a significant reduction in catheter-related bloodstream infection (p = .03). Model expansion to include intrajugular site was significant by a likelihood ratio test [2(log likelihood diff) = 4.26 P<.05 chi2(1)]
Conclusions:
The use of antiseptic triple-lumen catheters may substantially reduce catheter-related bloodstream infections in an intensive care population and may be subsequently associated with a decrease in length of stay.