Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wear Debris in Total Joint Replacements.

Jacobs1, Shanbhag, Glant

  • 1Rush-Presbyterian-St. Luke's Medical Center, Chicago.

The Journal of the American Academy of Orthopaedic Surgeons
|July 1, 1994
PubMed
Summary

Prosthetic implant wear generates debris, causing bone loss around artificial joints. Minimizing polyethylene wear is key to improving the longevity of total joint replacements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Teeth of Old Age.

The American journal of dental science·2019
Same author

Ulcerated Legs : Their Care and Cure.

The Hospital·2018
Same author

Observations on the Topical Pathology of the Neuralgiæ.

Provincial medical journal and retrospect of the medical sciences·2011
Same author

A lament for art in/of medicine.

Journal of primary health care·2010
Same author

DISCUSSION ON THE TREATMENT BY PHYSICAL METHODS OF MEDICAL DISABILITIES INDUCED BY THE WAR.

Proceedings of the Royal Society of Medicine·2009
Same author

Fatty acid compositions of gonadal material and diets of the sea urchin, Psammechinus miliaris: trophic and nutritional implications.

Journal of experimental marine biology and ecology·2000

Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Immunology

Background:

  • In vivo degradation of prosthetic implant materials is a primary limitation in total joint arthroplasty durability.
  • Implant wear generates particulate debris, stimulating adverse host responses and periprosthetic bone loss.
  • This bone loss, known as osteolysis, compromises implant fixation and bone stock.

Purpose of the Study:

  • To review the mechanisms of implant degradation and the host response to particulate debris.
  • To discuss the pathogenesis of osteolysis in the context of prosthetic joint wear.
  • To identify strategies for minimizing polyethylene wear in total joint arthroplasty.

Main Methods:

  • Review of existing literature on implant degradation and osteolysis.

Related Experiment Videos

  • Analysis of wear particle characteristics, particularly submicron polyethylene particles.
  • Examination of factors influencing polyethylene wear, including material quality and implant design.

    • Main Results:

    • Submicron polyethylene particles are the predominant wear particles in uncemented hip replacements.
    • Polyethylene wear can be reduced through improved material quality, optimized femoral head size, and enhanced modular connection design.
    • Understanding osteolysis mechanisms is crucial for developing preventive strategies.

    Conclusions:

    • Minimizing polyethylene wear is essential for enhancing the durability of total joint arthroplasty.
    • Strategies such as improving polyethylene quality and implant design can mitigate wear-induced osteolysis.
    • Further research into osteolysis pathogenesis will drive the development of effective preventive measures.