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Related Experiment Videos

Integration of a hematopoietic progenitor cell program using the ACT/DB database system.

P L Perrotta1, P M Nadkarni

  • 1Department of Pathology, University Hospital, State University of New York Stony Brook, 11794-7300, USA. pperrott@path.som.sunysb.edu

Computer Methods and Programs in Biomedicine
|March 10, 2000
PubMed
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A new software system monitors patients undergoing hematopoietic progenitor cell therapy for cancer. This system captures all data from cell collection to engraftment, ensuring quality control for complex clinical trials.

Area of Science:

  • Hematology
  • Oncology
  • Bioinformatics

Background:

  • Hematopoietic progenitor cell (HPC) infusion post-chemotherapy is a standard treatment for hematological malignancies and solid tumors.
  • Monitoring patients in experimental HPC therapy protocols presents complex data management challenges.
  • Integrating diverse data requirements is crucial for the success of complex therapeutic trials.

Purpose of the Study:

  • To develop a comprehensive software system for monitoring patients undergoing HPC therapy.
  • To ensure quality assurance and quality control throughout the data management process.
  • To leverage web-based technology for improved data integration and accessibility.

Main Methods:

  • Development of a client-server database system (ACT/DB) using Microsoft Access, Oracle, and SQL Server.

Related Experiment Videos

  • Implementation of data entry forms and reports with a focus on quality assurance and control.
  • Modification of the ACT/DB system for deployment on the Internet to utilize web-based technology.

    • Main Results:

    • The software system captures comprehensive data across all phases of HPC therapy: mobilization, collection, processing, infusion, and engraftment kinetics.
    • The system incorporates robust quality assurance and quality control functionalities.
    • The web-enabled system facilitates the integration of diverse data requirements for clinical trials.

    Conclusions:

    • A comprehensive, web-based software system effectively monitors patients undergoing HPC therapy.
    • The developed system enhances data management, quality control, and integration for complex clinical trials.
    • Information technology plays a vital role in supporting advanced cancer therapies and research.