Do horizontal cells contribute to the rabbit ERG?

An increase in the amplitude of horizontal cell (HC) potentials, a decrease in the extracellular potassium around the photoreceptors and an increase in the PIII component of the ERG that occur with increasing light stimulus intensity are shown to be concomitant occurrences, which could, therefore, be causally related. With high intensity light stimuli the PIII component is prominent and the HC potentials exhibit an afterpotential. Within the range of intensities tested the peak times of the HC afterpotentials coincide with the peak times of PIII. This indicates the likelihood that the HC potential contributes to the PIII, although these results do not allow a quantitative assessment of the contribution of HC potentials to the PIII-component.