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A case of eosinophilic cystitis in a 5-year-old boy
1Department of Urology, Kanagawa Children s Medical Center, Yokohama, Japan.
Insights
Eosinophilic cystitis (EC), a rare childhood disease, was diagnosed in a 5-year-old boy via open biopsy. Treatment with pemirolast potassium and monitoring eosinophil cationic protein (ECP) showed ECP to be a suitable marker for EC.
Area of Science:
- Pediatric Urology
- Allergy and Immunology
- Gastroenterology
Background:
- Eosinophilic cystitis (EC) is an uncommon inflammatory bladder condition in pediatric patients.
- Diagnosis often requires invasive procedures, highlighting the need for reliable diagnostic markers.
Observation:
- A 5-year-old boy presented with symptoms suggestive of EC.
- An open biopsy was necessary to confirm the diagnosis of eosinophilic cystitis.
- The patient was subsequently treated with pemirolast potassium.
Findings:
- Serum and urine eosinophil cationic protein (ECP) levels were monitored post-treatment.
- Eosinophil cationic protein (ECP) demonstrated utility as an appropriate marker for assessing EC activity.
- The patient's response to pemirolast potassium was evaluated through ECP levels.
Implications:
- This case underscores the diagnostic challenges of EC in children.
- ECP monitoring offers a potential non-invasive method for tracking treatment response in EC.
- Further research into EC pathogenesis and management is warranted.
Abstract:
Eosinophilic cystitis (EC) is rather an uncommon disease in childhood. A case of EC in a 5-year-old boy, in which open biopsy was needed for final diagnosis, is reported. After diagnosis, he was treated with pemirolast potassium followed-up with eosinophil cationic protein (ECP) in serum and urine. Eosinophil cationic protein is an appropriate marker of EC.