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The protein data bank. Bridging the gap between the sequence and 3D structure world
J L Sussman1, E E Abola, D Lin
1Biology Department, Brookhaven National Laboratory, Upton, NY 11973-5000, USA.
Genetica
|March 11, 2000
Summary
The Protein Data Bank (PDB) archives 3D structures of biological macromolecules, serving researchers globally for over 27 years. It offers easy data submission and examination tools for scientific advancement.
Area of Science:
- Structural biology
- Biochemistry
- Molecular biology
Background:
- The Protein Data Bank (PDB) is a critical resource for structural biology.
- It has a 27-year history of serving a global scientific community.
Observation:
- The PDB contains approximately 9000 experimentally determined 3D structures.
- Data can be submitted using the AutoDep tool in PDB or mmCIF format.
- The 3DB Browser provides convenient data examination.
Findings:
- The PDB facilitates access to vast amounts of structural data.
- WWW-based tools simplify data deposition and retrieval.
- Global collaborative centers support data archiving and distribution.
Implications:
- Enables researchers worldwide to access and utilize crucial structural data.
- Supports advancements in understanding biological processes at a molecular level.
- Promotes collaboration and data sharing within the scientific community.