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[Study on biliary motility in cirrhotic patients with portal hypertension]
1Department of gastroenterology, The Second Hospital of Xi'an Medical University, Xi'an 710004, China.
Objective:
To study biliary motility in cirrhotic patients with portal hypertension and analyze the relationship between these biliary motility and the degree of liver function.
Methods:
Biliary motility function was detected in 40 patients with portal hypertension and 30 normal controls by using quantitative hepatobiliary scintigraphy.
Results:
The rate of dysfunction of gallbladder in cirrhotic patients was 52.5%, and it was significantly higher than that in controls (chi(2)=11.92, P<0.01). Compared with the normal controls, the bile's transit in biliary duct of cirrhotic patients was slower (t=11.09, P<0.01), the time of gallbladder visualization became longer (t=5.65, P<0.01), and the gallbladder emptying time was markedly prolonged (t=2.10, P<0.05). A correlation was also seen between these biliary motility and the degree of liver function.
Conclusion:
Cirrhotic patients with portal hypertension often have abnormal motility of gallbladder and biliary duct.