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Neurotrophins: neurotrophic modulation of neurite growth
1School of Biology, Bute Medical Buildings, University of St. Andrews, St. Andrews, KY16 9TS, UK. amd2@st-and.ac.uk.
Current Biology : CB
|March 14, 2000
Abstract:
As well as regulating neuronal survival, neurotrophins control the growth of axons and dendrites. New light has been shed on the mechanism of this latter control process by the discovery that the common neurotrophin receptor p75(NTR) interacts in a ligand-dependent manner with RhoA, a known regulator of actin assembly.