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Updated: Aug 30, 2026

In Vitro and In Vivo Models to Study Corneal Endothelial-mesenchymal Transition
Published on: August 20, 2016
[Comparative evaluation of corneal endothelial cells after extracapsular cataract extraction with PMMA and
Purpose:
Comparison of endothelial cells density in eyes after PMMA and heparin-surface-modified lenses (HSfM1) implantation.
Material And Methods:
58 patients (26 male and 32 female) aged from 36 to 89 years. In 30 patients PMMA lenses produced by Pharmacia, Storz and Alcon and in 28 HSM (Pharmacia) lenses were implanted, after ECCE.
Results:
Percentage loss of endothelial cells in eyes with PMMA lenses was 8.61% after month and 13.56% 6 months post-operatively. In eyes with HSM lenses endothelial cell loss was 8.44% and 13.55% respectively.
Conclusion:
Loss of corneal endothelial cells in eyes with PMMA lenses is almost the same in eyes with HSM lenses.

