Related Experiment Video

Updated: Oct 21, 2026

Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells
07:55

Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells

Published on: June 21, 2019

A brief review of the concepts related to certain modern analytical methods and their use in medical science

W Burnett, C H Kennard

    The Australian and New Zealand Journal of Surgery
    |November 1, 1976
    PubMed

    More Related Videos

    Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics11:02

    Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

    Published on: November 29, 2024

    Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods05:34

    Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

    Published on: June 6, 2025

    Related Concept Videos

    MALDI-TOF Mass Spectrometry01:19

    MALDI-TOF Mass Spectrometry

    Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
    Applications Of NMR In Biology01:25

    Applications Of NMR In Biology

    Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
    The...
    Development of Analytical Methods01:21

    Development of Analytical Methods

    An analytical methodology can be divided into four sequential steps: technique, method, procedure, and protocol. A technique is a scientific principle that rationalizes a specific phenomenon through chemical measurements. Adapting a technique for analyzing a sample of interest is termed a method. The procedure outlines the directions for performing the analysis via an analytical method. The protocol is the detailed guidelines on the procedure, which should be strictly followed to obtain the...
    Measurement of Bioavailability: Pharmacodynamic Methods01:20

    Measurement of Bioavailability: Pharmacodynamic Methods

    Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.
    Therapeutic Drug Monitoring: Drug Analysis Methods01:26

    Therapeutic Drug Monitoring: Drug Analysis Methods

    Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
    Rapid Identification of Pathogens01:25

    Rapid Identification of Pathogens

    MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...