Maternal nutritional status and dietary supplementation and the growth of suckling infants

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...

Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.

The sense of taste begins developing before birth and is shaped by biological predispositions and early experience. During pregnancy, flavors from foods consumed by the mother can enter the amniotic fluid, exposing the fetus to different flavors. These prenatal experiences may contribute to food preferences after birth.Prenatal and Breastfeeding InfluencesAfter birth, flavors from a mother’s diet can also pass into breast milk. Repeated exposure to these flavors during breastfeeding may make...

Physical growth is especially rapid during the first three years of life, with the greatest rate in the first few months after birth. Although children continue to gain height and weight throughout infancy and toddlerhood, the rate of growth gradually slows during the second and third years. At most ages, boys are typically slightly taller and heavier than girls, reflecting a common pattern of early physical development.Changes in Body ProportionsAs infants become toddlers, their body...

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...