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The impact of tissue engineering on dentistry
1Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Md. 20892, USA.
Journal of the American Dental Association (1939)
|March 15, 2000
Summary
Tissue engineering offers innovative solutions for repairing tissues and creating bioartificial organs. This field is poised to significantly impact dental practice, particularly in mineralized tissue regeneration and oral wound healing.
Area of Science:
- Regenerative Medicine
- Biomaterials Science
- Biotechnology
Background:
- Tissue engineering is an emerging field focused on repairing damaged tissues and developing bioartificial organs.
- Key strategies and components of tissue engineering are reviewed, highlighting passive and inductive approaches.
- Examples of preclinical and clinical advancements, including dental implants and molecular signaling, are presented.
Purpose of the Study:
- To provide a comprehensive review of tissue engineering principles and applications.
- To discuss the current state and future potential of tissue engineering in various medical fields.
- To explore the specific implications of tissue engineering for dental practice.
Main Methods:
- Review of existing literature on tissue engineering strategies.
- Analysis of preclinical and clinical case studies.
- Discussion of passive and inductive tissue engineering approaches.
Main Results:
- Tissue engineering utilizes diverse strategies, including passive and inductive methods.
- Significant progress has been made in preclinical and clinical applications.
- Dental implants and molecular signaling represent key advancements.
Conclusions:
- Tissue engineering is expected to revolutionize dental practice within 25 years.
- The primary impact will be in the repair and replacement of mineralized tissues.
- Enhanced oral wound healing and adjunctive gene transfer are anticipated outcomes.