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Updated: Aug 7, 2026

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease
Published on: December 20, 2017
[Systemic enzyme therapy in chronic glomerulonephritis]
Aim:
To try polyenzyme drug vobenzim in chronic glomerulonephritis (CGN).
Materials And Methods:
174 CGN patients were randomized into 2 groups. The study group of 39 patients received conventional pathogenetic treatment plus vobenzim (initial dose 18-24, maintenance 12-15 dragees a day). Control group of 135 patients were given only pathogenetic therapy. 67 patients appeared ineligible.
Results:
3-6 months after the treatment the response was seen in 61.5% patients of the study and 17.8% patients of the control group. Side effects of vobenzim in CGN treatment were absent.
Conclusion:
Enzyme therapy with vobenzim in CGN is safe and effective.
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