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Antibodies to enteric adenoviruses (Ad40 and Ad41) in sera from Iranian children

H Saderi1, M H Roustai, F Sabahi

  • 1Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran. saderi_h@netics.modares.ac.ir

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
|March 18, 2000
PubMed

Insights

Enteric adenoviruses cause severe gastroenteritis in children. This study found antibodies to these viruses in about half of Iranian children, indicating common infections.

Area of Science:

  • Virology
  • Pediatric Infectious Diseases
  • Epidemiology

Background:

  • Enteric adenoviruses are known to cause severe gastroenteritis in children.
  • Epidemiologic and serologic data support this association.

Purpose of the Study:

  • To determine the prevalence of enteric adenovirus infection in Iran.
  • To assess the serologic evidence of enteric adenovirus exposure in Iranian children.

Main Methods:

  • Sera from 127 healthy Iranian children up to 7 years old were analyzed.
  • Antibodies to enteric adenoviruses were detected using neutralization tests.
  • Samples were collected between 1993 and 1994.

Main Results:

  • Antibodies to enteric adenoviruses were detected in approximately 50% of the tested sera.
  • This indicates significant exposure to these viruses in the study population.

Conclusions:

  • Enteric adenovirus infection is common among children in Iran.
  • The findings highlight the public health importance of enteric adenovirus in pediatric populations in the region.
Abstract

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