In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae
S Strigl1, P M Roblin, T Reznik
1Division of Infectious Diseases, Department of Pediatrics, State University of New York Health Science Center at Brooklyn, Brooklyn, New York 11203-2098, USA.
Antimicrobial Agents and Chemotherapy
|March 18, 2000
Abstract:
The in vitro activities of ABT 773, telithromycin (HMR 3647), azithromycin, clarithromycin, erythromycin, and levofloxacin were tested against 20 strains of Chlamydia pneumoniae. The MIC at which 90% of the isolates were inhibited and the minimal bactericidal concentration at which 90% of the isolates were killed by ABT 773 were 0.015 microg/ml (range, 0.008 to 0.015 microg/ml). ABT 773 was the most active antibiotic tested in this study.
