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Published on: November 28, 2018
Long term outcome of percutaneous mitral balloon valvotomy in patients aged 70 and over
N Sutaria1, A T Elder, T R Shaw
1Department of Cardiology, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK.
Insights
Percutaneous mitral balloon valvotomy offers significant hemodynamic improvement and symptomatic relief in elderly patients over 70. This safe procedure provides a valuable palliative option for those unsuitable for surgery.
Area of Science:
- Cardiology
- Interventional Cardiology
- Geriatric Medicine
Background:
- Severe mitral stenosis in elderly patients presents a significant clinical challenge.
- Surgical intervention for mitral stenosis in patients over 70 is often associated with high risk due to comorbidities.
- Percutaneous mitral balloon valvotomy (PMBV) has emerged as a less invasive alternative.
Purpose of the Study:
- To evaluate the immediate hemodynamic effects of PMBV.
- To assess the long-term symptomatic benefits of PMBV in patients aged 70 years and older.
- To determine the safety and efficacy of PMBV as a palliative treatment in this population.
Main Methods:
- A prospective study was conducted at a tertiary referral center.
- Eighty patients aged 70 and above underwent PMBV.
- Hemodynamic parameters were measured pre- and post-procedure, with follow-up ranging from 1 to 10 years.
Main Results:
- PMBV resulted in an 89% increase in mitral valve area (from 0.84 to 1.59 cm²).
- Complication rates were low, with only two patients experiencing long-term major sequelae.
- At 5 years, 25% of surgically unsuitable patients and 36% of suitable patients remained free from valve replacement and showed symptom improvement.
Conclusions:
- PMBV is a safe and effective palliative procedure for elderly patients with mitral stenosis, particularly those unsuitable for surgery.
- The procedure offers significant hemodynamic improvement and long-term symptomatic benefit.
- While echo score is used to predict outcomes, it is an imperfect predictor of hemodynamic improvement.
Objective:
To assess the immediate haemodynamic improvement and long term symptomatic benefit of percutaneous mitral balloon valvotomy in patients aged over 70 years.
Design:
Pre- and postprocedure haemodynamic data and follow up for 1 to 10 years by clinic visit or telephone contact.
Setting:
Tertiary referral centre in Scotland.
Subjects:
80 patients age 70 and over who had mitral balloon dilatation: 55 were considered unsuitable for surgical treatment because of frailty or associated disease. In an additional four patients mitral dilatation was not achieved.
Main Outcome Measures:
Increase in valve area after balloon dilatation and survival, freedom from valve replacement, and symptom class at follow up.
Results:
Mean (SD) valve area increased by 89% from 0.84 (0.28) to 1. 59 (0.67) cm(2). There was a low rate of serious complications, with only two patients having long term major sequelae. Of 55 patients unsuitable for surgical treatment, 28 (51%) were alive without valve replacement and with improvement by at least one symptom class at one year, and 14 (25%) at five years. In the 25 patients considered suitable for surgical treatment, 16 (64%) achieved this outcome at one year and nine (36%) at five years.
Conclusions:
Percutaneous mitral balloon valvotomy is a safe and useful palliative procedure in elderly patients who are unsuitable for surgery. Balloon dilatation should also be used for elderly patients whose valve appears suitable for improvement by commissurotomy, but echo score is an imperfect predictor of haemodynamic improvement.
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