Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The atrioventricular junctions in Ebstein malformation.

S Y Ho1, D Goltz, K McCarthy

  • 1Paediatrics, National Heart and Lung Institute, Royal Brompton Campus, Imperial College of Science, Technology and Medicine, Dovehouse Street, London SW3 6LY, UK. yen.ho@ic.ac.uk

Heart (British Cardiac Society)
|March 18, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multidimensional Analysis of the Adult Human Heart in Health and Disease using Hierarchical Phase-Contrast Tomography (HiP-CT).

bioRxiv : the preprint server for biology·2023
Same author

Histological changes in the left and right ventricle in hearts with Ebstein's malformation and tricuspid valvar dysplasia: A morphometric study of patients dying in the fetal and perinatal periods.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Complex left atrial cor triatriatum associated with supravalvar mitral membrane, coronary sinus defect and persistent left superior caval vein. 3D echocardiography navigates surgeon to successful repair.

International journal of cardiology·2014
Same author

Assessment of fitness for purpose of an insect bioassay using the desert locust (Schistocerca gregaria L.) for the detection of paralytic shellfish toxins in shellfish flesh.

Toxicon : official journal of the International Society on Toxinology·2006
Same author

Early fetal diagnosis of monochorionic twins concordant for hypoplastic left heart syndrome.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2004
Same author

Concordance for hypoplastic left heart syndrome in a monochorionic twin pregnancy.

Heart (British Cardiac Society)·2003
Same journal

Feasibility of early double sequential defibrillation in out-of-hospital cardiac arrest: the double-D randomised pilot trial.

Heart (British Cardiac Society)·2026
Same journal

Correspondence on 'When a patent foramen ovale becomes pathological' by Saji and Ohara.

Heart (British Cardiac Society)·2026
Same journal

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026
Same journal

Optimal timing of aspirin discontinuation after acute coronary syndrome treated with percutaneous coronary intervention: a systematic review and meta-analysis.

Heart (British Cardiac Society)·2026
Same journal

Importance of rating: the impact of establishing age and sex normative values for left ventricular strain rate.

Heart (British Cardiac Society)·2026
Same journal

Man in his 40s with palpitations.

Heart (British Cardiac Society)·2026
See all related articles

Structural abnormalities in the atrioventricular conduction system were identified in hearts with Ebstein malformation, potentially explaining conduction issues. The right atrioventricular junction showed better development than expected.

Area of Science:

  • Cardiovascular Anatomy
  • Cardiac Electrophysiology
  • Congenital Heart Disease

Background:

  • Ebstein's malformation is a congenital heart defect affecting the tricuspid valve and right ventricle.
  • Conduction abnormalities are frequently observed in patients with Ebstein's malformation.
  • Understanding the anatomical basis of these conduction abnormalities is crucial for patient management.

Purpose of the Study:

  • To investigate the anatomical structure of the right atrioventricular junction and its specialized conduction system in Ebstein's malformation.
  • To identify potential anatomical substrates contributing to conduction abnormalities in this condition.

Main Methods:

  • Gross and histological examination of five heart specimens with Ebstein's malformation.
  • Detailed analysis of the right atrioventricular junction and associated conduction pathways.

Related Experiment Videos

Main Results:

  • The right atrioventricular junction showed variations in its surface marking and fibrofatty tissue separation.
  • Accessory atrioventricular, nodoventricular, and fasciculo-ventricular connections were identified.
  • The compact atrioventricular node was located closer to the coronary sinus than usual.
  • Hypoplasia or absence of the right bundle branch was noted in a significant proportion of specimens.

Conclusions:

  • The parietal atrioventricular junction in Ebstein's malformation may be more developed than previously recognized.
  • Structural abnormalities within the atrioventricular conduction system are present and likely contribute to observed conduction disturbances.
  • These findings provide insights into the electrophysiological consequences of Ebstein's malformation.