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Related Experiment Videos

[The multifood allergy syndrome].

D A Moneret-Vautrin1, G Kanny, L Guérin

  • 1Service de Médecine Interne, Immunologie Clinique et Allergologie, Hôpital Central, Nancy.

Allergie Et Immunologie
|March 21, 2000
PubMed
Summary
This summary is machine-generated.

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Multiple food intolerances affect over 40% of infants, presenting with severe atopic dermatitis or enterocolitis. Diagnosis involves oral food challenges, with amino-acid formulas improving outcomes for affected infants.

Area of Science:

  • Pediatric Allergy and Immunology
  • Gastroenterology
  • Dermatology

Context:

  • Increasing diagnosis of multiple food intolerances in infants and young children.
  • Affects over 40% of infants under one year old.
  • Characterized by severe atopic dermatitis (SCORAD > 50), enterocolitis, or failure to thrive.

Purpose:

  • To summarize the current understanding of multiple food intolerances in infants and young children.
  • To highlight diagnostic methods and contributing factors.
  • To discuss the impact of therapeutic interventions.

Summary:

  • Common allergens include milk, egg, soy, and wheat, though others can be involved.
  • Diagnosis relies on standardized oral food challenges.
  • Etiopathogenic factors include atopy, intestinal hyperpermeability, early food diversification, and prolonged breastfeeding.

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Impact:

  • Amino-acid based formulas have significantly improved the clinical course and outcomes.
  • Understanding these factors aids in better management and treatment strategies.
  • Highlights the long-lasting and complex nature of the syndrome.