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Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Kingella kingae infections in children.
1Department of Paediatrics, Gold Coast Hospital, Southport, Queensland, Australia.
Journal of Paediatrics and Child Health
|March 21, 2000
Summary
Kingella kingae infections in children are more common than previously thought. Early detection and appropriate antibiotic treatment, such as cephalosporins, are crucial for managing these pediatric infections.
Area of Science:
- Pediatric Infectious Diseases
- Bacteriology
Background:
- Kingella kingae is an increasingly recognized cause of invasive pediatric infections.
- Awareness of this pathogen is crucial for timely diagnosis and treatment.
Observation:
- Four cases of Kingella kingae infection in children are presented.
- Literature review conducted from 1983-1998 identified osteoarticular infections, bacteremia, and endocarditis.
Findings:
- Isolation of Kingella kingae can be challenging; enriched blood culture systems improve recovery.
- Most isolates are susceptible to beta-lactam antibiotics, though resistance exists.
Implications:
- Kingella kingae infections are likely underdiagnosed in pediatric populations.
- Active pursuit of Kingella kingae in suspected osteoarticular infections is recommended.
- Empiric therapy with third-generation cephalosporins is advised pending susceptibility results.
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