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Updated: Jul 19, 2026

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals
Published on: March 30, 2017
Design, development and performance of a novel multidose dry-powder inhaler
M Parry-Billings1, R N Boyes, L M Clisby
1R&D at Innovata Biomed Ltd, Respiratory Division of ML Laboratories plc, St Albans, UK. mparryb@aol.com
Abstract:
The authors describe the design and development of a breath-actuated multidose dry-powder inhaler and summarize the in vitro and in vivo data demonstrating its robustness and performance in the laboratory and during clinical use. Drugs for the treatment of asthma--including budesonide, beclomethasone dipropionate and salbutamol--when formulated with lactose powder as a carrier and dispensed via this device, have exhibited clinical efficacy and safety profiles comparable with standard pressurized metered-dose inhalers and dry-powder formulations.
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