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Acute mesenteric infarction caused by small vessel disease

Acta Chirurgica Scandinavica. Supplementum
|January 1, 1976
PubMed

Insights

Acute mesenteric infarction in a patient was caused by small vessel disease. Surgical intervention led to recovery, revealing intimal hyperplasia and atherosclerosis as key factors.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Pathology

Background:

  • Acute mesenteric infarction is a critical condition often associated with large vessel thrombosis.
  • Small vessel disease as a primary cause of mesenteric infarction is less commonly reported.

Observation:

  • A case of acute mesenteric infarction was successfully treated with extensive bowel resection.
  • The patient required two surgical operations for management.

Findings:

  • Histopathological examination of resected bowel revealed intimal hyperplasia and atherosclerosis in small mesenteric arteries.
  • Laboratory findings included thrombocytosis and increased platelet aggregation, suggesting a hypercoagulable state.

Implications:

  • This case highlights small vessel disease, specifically intimal hyperplasia and atherosclerosis, as a potential cause of acute mesenteric infarction.
  • Hypercoagulability, evidenced by thrombocytosis and platelet aggregation, likely contributed to the thrombotic event.
  • Understanding these mechanisms is crucial for diagnosing and managing mesenteric ischemia, particularly in cases without large vessel occlusion.

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