Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obstructive uropathy.

W S McDougal1, W S Kerr

  • 1Department of Urology, Massachusetts General Hospital, Boston 02114, USA.

Current Opinion in Urology
|March 22, 2000
PubMed
Summary
This summary is machine-generated.

Recent molecular biologic advances have significantly improved understanding of obstructive uropathy pathophysiology, focusing on apoptosis and gene expression. However, research on fetal kidney development affected by this condition has seen no major progress.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing prostate cancer growth with citrate measured by intact tissue proton magnetic resonance spectroscopy.

Prostate cancer and prostatic diseases·2012
Same author

A CASE OF OTITIC MENINGITIS AND CEREBELLAR ABSCESS, WITH RECOVERY.

British medical journal·2010
Same author

Studies on the differentiation pathway and growth characteristics of epithelial culture cells of the human prostate.

Prostate cancer and prostatic diseases·2004
Same author

Effect of keratinocyte growth factor and activin on cell growth in the human prostatic cancer cell line LNCaP.

World journal of urology·2004
Same author

Regulation of keratinocyte growth factor receptor and androgen receptor in epithelial cells of the human prostate.

The Journal of urology·2001
Same author

Radio-frequency ablation of renal cell carcinoma: early clinical experience.

Radiology·2000
Same journal

Role and relevance of genetic testing in patients with kidney stones: a review from EAU Section of Endourology.

Current opinion in urology·2026
Same journal

Advances in evaluating and delivering nontechnical skills training: The use of simulation, robotics, artificial intelligence and virtual reality.

Current opinion in urology·2026
Same journal

Educating for a sustainable future: faculty and student perspectives and a review of environmental sustainability in medical education - an EAU endourology study.

Current opinion in urology·2026
Same journal

Shaping the future of endourology: role of education, simulation and uro-technology: a scoping review by the EAU Section of Endourology.

Current opinion in urology·2026
Same journal

A review of emerging technologies and techniques for percutaneous nephrolithotomy access.

Current opinion in urology·2026
Same journal

Artificial intelligence in kidney cancer: a review of clinical applications across the disease spectrum.

Current opinion in urology·2026
See all related articles

Area of Science:

  • Urology
  • Molecular Biology
  • Pathophysiology

Background:

  • Obstructive uropathy is a significant clinical condition.
  • Understanding its molecular mechanisms is crucial for effective treatment.
  • Previous research has laid the groundwork for current investigations.

Purpose of the Study:

  • To summarize recent advances in the pathophysiology of obstructive uropathy.
  • To highlight key molecular biologic findings, including apoptosis and gene expression.
  • To identify areas lacking recent progress, such as fetal kidney development.

Main Methods:

  • Review of recent scientific literature.
  • Analysis of molecular biologic pathways involved in obstructive uropathy.
  • Identification of key genes and cellular processes.

Related Experiment Videos

Main Results:

  • Significant advances in understanding obstructive uropathy pathophysiology.
  • Key molecular insights into apoptosis and transforming growth factor-beta (TGF-beta).
  • Definition of the expression patterns of specific genes relevant to the condition.

Conclusions:

  • Molecular biologic research has greatly advanced the understanding of obstructive uropathy.
  • Apoptosis, TGF-beta, and gene expression are critical areas of focus.
  • Further research is needed on the impact of obstructive uropathy on fetal kidney development.