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Related Experiment Videos

Biomaterials in the face: benefits and risks.

A K Gosain1, J A Persing

  • 1Department of Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

The Journal of Craniofacial Surgery
|March 22, 2000
PubMed
Summary

This review explores facial biomaterials for reconstruction, covering current methods and future tissue engineering. It discusses bone grafts, implants, and novel approaches for facial skeleton repair.

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Area of Science:

  • Maxillofacial Surgery
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Review of a biomaterials symposium focused on facial reconstruction.
  • Exploration of current reconstructive techniques for the facial skeleton.
  • Inclusion of autogenous bone and various biomaterials in facial repair.

Framework:

  • Assessment of biomaterials for facial reconstruction, including bone grafts, methyl methacrylate, demineralized bone, and hydroxyapatite.
  • Evaluation of biomaterials for rigid fixation (metallic, bioabsorbable implants) and facial augmentation (porous polyethylene, hard-tissue replacement, ceramics).
  • Discussion of biofilm formation on implants and strategies to induce bone formation.

Implementation:

  • Utilizing autogenous bone grafts for facial skeleton reconstruction.

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  • Employing synthetic biomaterials like methyl methacrylate, hydroxyapatite, and porous polyethylene.
  • Investigating advanced techniques such as cytokine interaction, gene transfer, and tissue engineering for bone and cartilage regeneration.

    • Implications:

    • Potential for improved reconstructive techniques in maxillofacial surgery.
    • Advancements in tissue engineering for creating patient-specific bone and cartilage.
    • Enhanced understanding of biomaterial integration and host response in facial implants.