Classification of antiarrhythmic agents and the two laws of pharmacology

Oscillations of cardiac wave length and proarrhythmia.

Naunyn-Schmiedeberg's archives of pharmacology·2010

Ultrafast sodium channel block by dietary fish oil prevents dofetilide-induced ventricular arrhythmias in rabbit hearts.

American journal of physiology. Heart and circulatory physiology·2008

Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia.

Cardiovascular research·2001

Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic.

Circulation·2001

Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes.

Circulation·1995

Computer aided development of antiarrhythmic agents with class IIIa properties.

Journal of cardiovascular electrophysiology·1994

Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity.

Cardiovascular research·2026

Endothelial TLR4 coordinates angiogenesis and inflammation through a CXCR2-neutrophil-oxidative axis.

Cardiovascular research·2026

Healthy bone marrow transplantation into hypertriglyceridemic rats improves cardiac reparative fibrosis post-myocardial infarction.

Cardiovascular research·2026

Spatial heterogeneity of APD under long QT conditions: characterisation and relationship to sinus activation sequence.

Cardiovascular research·2026

A human engineered mini-heart platform for mimicking ventricular pump function.

Cardiovascular research·2026

Beyond glucose: metabolic substrate provision enhances cardiac energetics, function and stability ex vivo: a simple recipe for healthier hearts?

Cardiovascular research·2026

Orphan drug regulation: a global comparison of the United States Food and Drug Administration, European Medicines Agency, and Japanese Pharmaceuticals and Medical Devices Agency approaches.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria·2026

Distinct EEG functional network alterations in Parkinson's disease and multiple system atrophy.

NeuroImage. Clinical·2026

Hyaluronic acid in Peyronie's disease: focus on injection procedures and clinical practice.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica·2026

Current perspectives on the pharmacologic treatment of boys and adolescents with congenital hypogonadotropic hypogonadism.

Expert opinion on pharmacotherapy·2026

Wound/Pressure Ulcer/Burn Guidelines (2023)-3 Guidelines for the Diagnosis and Treatment of Diabetic Skin Ulcer/Gangrene (3rd Edition).

The Journal of dermatology·2026

A New Class of Drugs Approved in the United States for Hypertension: Aldosterone Synthase Inhibitors.

The American journal of medicine·2026

Related Experiment Videos

Classification of antiarrhythmic agents and the two laws of pharmacology

Related Concept Videos

Oscillations of cardiac wave length and proarrhythmia.

Ultrafast sodium channel block by dietary fish oil prevents dofetilide-induced ventricular arrhythmias in rabbit hearts.

Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia.

Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic.

Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes.

Computer aided development of antiarrhythmic agents with class IIIa properties.

Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity.

Endothelial TLR4 coordinates angiogenesis and inflammation through a CXCR2-neutrophil-oxidative axis.

Healthy bone marrow transplantation into hypertriglyceridemic rats improves cardiac reparative fibrosis post-myocardial infarction.

Spatial heterogeneity of APD under long QT conditions: characterisation and relationship to sinus activation sequence.

A human engineered mini-heart platform for mimicking ventricular pump function.

Beyond glucose: metabolic substrate provision enhances cardiac energetics, function and stability ex vivo: a simple recipe for healthier hearts?

Orphan drug regulation: a global comparison of the United States Food and Drug Administration, European Medicines Agency, and Japanese Pharmaceuticals and Medical Devices Agency approaches.

Distinct EEG functional network alterations in Parkinson's disease and multiple system atrophy.

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Classification of antiarrhythmic agents and the two laws of pharmacology

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