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Sry-negative XX true hermaphrodite in a Basset hound
M Hubler1, B Hauser, V N Meyers-Wallen
1Department of Reproduction, University of Zurich, Switzerland.
Theriogenology
|March 23, 2000
Abstract:
A true hermaphrodite was diagnosed in a 7-mo.-old Basset hound. The diagnosis was based on the clinical signs, the histology of the gonads and the karyogram. Additionally, the dog was tested for the Y-linked gene Sry, which was negative. The Basset hound presented here is compared to other XX sex reversed animals described in the literature. In man, XX sex reversal is a heterogenous condition. The pathogenesis in Sry-negative individuals is not understood. Thus Sry-negative animals could serve as an animal model of the human disease.