Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Malignant catatonia].

M de Entrambasaguas1, J L Sánchez, W Schonewille

  • 1Servicio de Neurología y Neurofisiología, Clínica Rotger, Palma de Mallorca, España.

Revista De Neurologia
|March 24, 2000
PubMed
Summary

Malignant catatonia, a severe syndrome potentially linked to decreased dopamine activity, can be effectively treated with early electroconvulsive therapy (ECT). This case highlights successful remission in a patient with idiopathic malignant catatonia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Exploratory analysis of the influence of cognitive reserve on the benefits of cognitive stimulation therapy in patients with sporadic late-onset Alzheimer's disease].

Revista de neurologia·2020
Same author

[Cognitive-behavioural group therapy for insomnia: evaluation of the results after its implementation in a health department].

Revista de neurologia·2020
Same author

A surge of light at the birth of a supernova.

Nature·2018
Same author

A Scheduled Program of Molecular Screening for Epstein-Barr Virus Decreases the Incidence of Post-transplantation Lymphoproliferative Disease in Pediatric Liver Transplantation.

Transplantation proceedings·2016
Same author

Influence of net energy content of the diets on productive performance and carcass merit of gilts, boars and immunocastrated males slaughtered at 120kg BW.

Meat science·2014
Same author

Variability between experts in defining the edge and area of the optic nerve head.

Archivos de la Sociedad Espanola de Oftalmologia·2013

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Malignant catatonia is associated with significantly reduced central dopaminergic activity.
  • Potential etiologies include medical, psychiatric, toxic-pharmacologic, or idiopathic origins.

Observation:

  • A 24-year-old male presented with seizures, progressing to severe catatonia, agitation, and paranoid ideation.
  • The patient developed aspiration pneumonia, requiring Intensive Care Unit (ICU) admission and prolonged management.
  • Diagnostic workup, including neuroimaging and laboratory tests, did not yield an etiological diagnosis.

Findings:

  • Electroencephalogram (EEG) initially showed focal, then generalized, theta and delta waves.
  • The patient received 27 sessions of electroconvulsive therapy (ECT) over three months, leading to remission of catatonic symptoms.
  • Final diagnosis was idiopathic malignant catatonia, with residual amnesia upon discharge.

Implications:

  • Management of malignant catatonia can be complex due to diverse etiologies and potential lethality.
  • Early initiation of electroconvulsive therapy (ECT) is crucial for favorable outcomes.
  • Successful treatment is contingent on the treatability of the underlying cause and absence of central nervous system structural lesions.

Related Experiment Videos