Related Experiment Videos
[Malignant Mesothelioma Registry from Piedmont. Incidence in 1990-1995]
C Ivaldi1, P Dalmasso, M Nesti
1Servizio Universitario di Epidemiologia dei Tumori (Registro dei Mesoteliomi Maligni del Piemonte) CPO-Piemonte, Azienda Ospedaliera S. Giovanni Battista, Torino.
Abstract:
This paper describes methods and results of the Piedmont Malignant Mesothelioma Registry. The Registry is active since 1990 and collects all histologically confirmed incident cases of malignant mesothelioma (m.m.) occurring in the residents of Piedmont. In the period 1990-95, 346 cases of pleural m.m. (211 males and 135 females) and 41 (28 males and 13 females) of peritoneal m.m. have been observed. Amongst the inhabitants of the Local Health Authority of Casale Monferrato, where manufacturing of cement asbestos has determined serious asbestos exposures both in the work place and general environment, there have been 105 pleural m.m. and 17 peritoneal m.m. (incidence rate were 15.6 for men and 13.0 for women and 3.6 for men and 0.6 for women respectively). Leaving out the Local Health Authority (LHA) of Casale Monferrato, the annual incidence rate in Piedmont (for 10(5) person-years, age standardised on the 1981 Italian population), has been 1.0 in men and 0.6 in women for the pleural m.m. (respectively 154 and 87 cases) and 0.09 and 0.06 for peritoneal m.m. (14 and 10 cases). Possible cases of m.m. (cytological and/or x-ray diagnosis) have been searched in the file of hospital admission and discharges (SDO) in 1994-95: 46 additional cases were found, with a 25% increase in incidence rates. The analysis of incidence according to geographical aggregations (defined according to the LHA borders) has identified, besides some already known important sources of exposures, as Casale Monferrato and the LHA of Lanzo (Balangero mine), other areas with excess of incidence as the LHA's of Galliate and Caluso which show an increased incidence of pleural m.m. in men or Vercelli and Chieri with increased incidence of pleural m.m. in women. These observation deserves further analysis.
Insights
The Piedmont Malignant Mesothelioma Registry identified 346 pleural and 41 peritoneal malignant mesothelioma cases from 1990-1995. High incidence rates were observed in areas with significant asbestos exposure, such as Casale Monferrato.
Area of Science:
- Epidemiology
- Environmental Health
- Oncology
Context:
- The Piedmont Malignant Mesothelioma Registry has monitored incident malignant mesothelioma (m.m.) cases since 1990.
- Asbestos exposure from cement manufacturing in Casale Monferrato has led to significant asbestos exposure in the workplace and general environment.
Purpose:
- To describe the methods and results of the Piedmont Malignant Mesothelioma Registry.
- To analyze the incidence of malignant mesothelioma in Piedmont, Italy, from 1990-1995.
- To identify geographical areas with excess incidence rates of m.m.
Summary:
- The registry recorded 346 pleural and 41 peritoneal m.m. cases between 1990-1995.
- Casale Monferrato showed high incidence rates (15.6 for men, 13.0 for women for pleural m.m.).
- Excluding Casale Monferrato, Piedmont's annual incidence rates were 1.0/10^5 person-years for men and 0.6/10^5 for women for pleural m.m.
Impact:
- Identified specific geographic areas with elevated m.m. incidence beyond known exposure sites.
- Highlighted the need for further analysis in areas like Galliate, Caluso, Vercelli, and Chieri.
- The study provides crucial data for understanding asbestos-related disease burdens and informing public health interventions.