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Published on: October 21, 2015
Recurrence of clival chordoma along the surgical pathway
N J Fischbein1, M J Kaplan, R A Holliday
1Department of Radiology, University of California, San Francisco 94143, USA.
Abstract:
Chordomas are locally aggressive malignant tumors of notochordal origin whose metastatic potential is increasingly recognized. Surgical pathway recurrence has been noted only rarely in the literature. We present three patients with clival chordomas whose sole or initial recurrence was along the pathway of prior surgical access. A characteristic mass found along the pathway of prior surgical access for resection of a chordoma should suggest recurrent chordoma.
Insights
Chordomas, rare notochordal tumors, can recur along surgical pathways. This study highlights this unusual recurrence pattern in three patients with clival chordoma.
Area of Science:
- Oncology
- Neurosurgery
- Pathology
Background:
- Chordomas are rare, locally aggressive malignant tumors originating from notochordal remnants.
- While metastatic potential is recognized, recurrence along surgical pathways is infrequently documented.
Observation:
- This report details three cases of clival chordoma.
- In these patients, the sole or initial tumor recurrence occurred along the trajectory of previous surgical intervention.
Findings:
- Recurrence of chordoma along the surgical pathway is a distinct possibility.
- A mass identified in the surgical access route should raise suspicion for chordoma recurrence.
Implications:
- Clinicians should consider surgical pathway recurrence in the differential diagnosis of clival masses post-chordoma resection.
- Awareness of this recurrence pattern may improve diagnostic accuracy and patient management for chordoma.

