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Related Concept Videos

Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Drug toxicity: Drug–Drug Interaction01:30

Drug toxicity: Drug–Drug Interaction

Drug–drug interactions can precipitate toxicity through multiple mechanisms. Absorption interactions alter how drugs enter the body, exemplified when ranitidine increases the absorption of basic drugs, while cholestyramine decreases the levels of propranolol. Protein binding interactions occur when drugs share the same binding sites on plasma proteins. Drugs like aspirin and warfarin, when bound in excess, can lead to increased free drug concentrations, enhancing the potential for...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...

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Related Experiment Video

Updated: Jul 14, 2026

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
07:34

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

Published on: April 11, 2012

Safety issues with herbal medicine.

J I Boullata1, A M Nace

  • 1Department of Pharmacy Practice, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, USA.

Pharmacotherapy
|March 24, 2000
PubMed
Summary

Pharmacists need to understand herbal medicine safety due to rising usage and potential risks. Staying informed about regulations and unexpected product effects is crucial for consumer protection.

Area of Science:

  • Pharmacology
  • Integrative Medicine
  • Public Health

Background:

  • Increasing public use of herbal medicines necessitates a focus on their safety profiles.
  • Pharmacists play a vital role in consumer health and safety regarding medicinal products.
  • Understanding the regulatory landscape of herbal products is key to assessing their safety.

Purpose of the Study:

  • To highlight the growing importance of pharmacist knowledge regarding herbal medicine safety.
  • To emphasize the need for awareness of regulations affecting herbal product safety.
  • To underscore the pharmacist's expanding role in consumer protection.

Main Methods:

  • Literature review of popular herbal products and their reported effects.
  • Analysis of regulatory frameworks governing herbal medicine marketing.

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Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

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Field Identification of Matricaria chamomilla using a Portable qPCR System
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Field Identification of Matricaria chamomilla using a Portable qPCR System

Published on: October 10, 2020

Related Experiment Videos

Last Updated: Jul 14, 2026

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
07:34

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

Published on: April 11, 2012

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Field Identification of Matricaria chamomilla using a Portable qPCR System
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Field Identification of Matricaria chamomilla using a Portable qPCR System

Published on: October 10, 2020

  • Examination of case studies detailing unexpected herbal product reactions.
  • Main Results:

    • Significant increase in the utilization of various herbal medicines globally.
    • Identification of numerous popular herbal products with documented adverse or unexpected effects.
    • Growing complexity in the regulatory oversight of herbal products.

    Conclusions:

    • Pharmacists require comprehensive knowledge of herbal medicine safety to effectively guide consumers.
    • Regulatory awareness is essential for pharmacists to mitigate potential risks associated with herbal products.
    • The pharmacist's role in safeguarding consumers from potential harm due to herbal medicines is expanding.