Redefining Rowell's syndrome

Area of Science:

• Rheumatology
• Dermatology
• Immunology

Background:

• Rowell's syndrome is a rare condition characterized by lupus erythematosus and erythema multiforme-like lesions.
• It is associated with specific immunological markers including speckled antinuclear antibodies, anti-La antibodies, and rheumatoid factor.

Observation:

• Two new cases of Rowell's syndrome are presented.
• A review of existing literature on diagnostic criteria for Rowell's syndrome was conducted.

Findings:

• Inconsistent findings in current diagnostic features were noted.
• A proposal for revised diagnostic criteria, incorporating major and minor criteria, is presented.

Implications:

• The proposed criteria aim to improve the diagnostic accuracy of Rowell's syndrome.
• This may lead to earlier and more consistent diagnosis and management of patients with this rare condition.