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Redefining Rowell's syndrome.

N C Zeitouni1, D Funaro, R A Cloutier

  • 1Centre Hospitalier Universitaire de Québec, Service de Dermatologie, Pavillon-Hôtel-Dieu de Québec, Canada. nzeitouni@SC3103.med.buffalo.edu

The British Journal of Dermatology
|March 24, 2000
PubMed
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Rowell's syndrome, a rare lupus erythematosus variant, presents with specific skin lesions and autoantibodies. This study proposes refined diagnostic criteria, distinguishing major and minor features for better identification of this distinct clinical entity.

Area of Science:

  • Rheumatology
  • Dermatology
  • Immunology

Background:

  • Rowell's syndrome is a rare condition characterized by lupus erythematosus and erythema multiforme-like lesions.
  • It is associated with specific immunological markers including speckled antinuclear antibodies, anti-La antibodies, and rheumatoid factor.

Observation:

  • Two new cases of Rowell's syndrome are presented.
  • A review of existing literature on diagnostic criteria for Rowell's syndrome was conducted.

Findings:

  • Inconsistent findings in current diagnostic features were noted.
  • A proposal for revised diagnostic criteria, incorporating major and minor criteria, is presented.

Implications:

  • The proposed criteria aim to improve the diagnostic accuracy of Rowell's syndrome.

Related Experiment Videos

  • This may lead to earlier and more consistent diagnosis and management of patients with this rare condition.