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Immunologic effects of yogurt.

S N Meydani1, W K Ha

  • 1Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging and the Department of Pathology, Sackler Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA. s_meydani_im@hnrc.tufts.edu

The American Journal of Clinical Nutrition
|March 25, 2000
PubMed
Summary

Yogurt consumption may boost the immune system, potentially enhancing resistance to diseases. Further research is needed to confirm these immunostimulatory effects in humans, especially in vulnerable groups like the elderly.

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Area of Science:

  • Immunology
  • Nutrition Science
  • Microbiology

Background:

  • Yogurt and lactic acid bacteria are studied for therapeutic effects on various diseases.
  • The immune system's role in these diseases suggests a potential immunostimulatory effect of yogurt.
  • Previous research, primarily in animal models, indicates yogurt may stimulate the immune system.

Purpose of the Study:

  • To review existing evidence on yogurt's immunostimulatory effects.
  • To identify limitations in current research methodologies.
  • To propose future research directions for substantiating yogurt's immune-enhancing potential.

Main Methods:

  • Review of existing scientific literature on yogurt and immune response.
  • Analysis of study designs, controls, and outcome measures in previous investigations.

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  • Identification of gaps and limitations in current research.

    • Main Results:

    • Existing studies generally support yogurt's immunostimulatory effects.
    • Significant limitations exist in study designs, controls, and duration.
    • In vitro immune indicators are often used, with limited in vivo data.

    Conclusions:

    • Yogurt consumption may enhance immune response, particularly in immunocompromised individuals.
    • Well-designed, randomized, placebo-controlled human studies are needed.
    • Future research should assess both in vivo and in vitro immune markers over adequate durations.