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Updated: Aug 11, 2026
OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
Initial experience with a modification of the follicle aspiration, sperm injection, and assisted rupture technique
P C Lin1, J F D'Amico, S T Nakajima
1University of Louisville School of Medicine, Louisville, Kentucky, USA.
Objective:
To establish cycle fecundity with a modification of the follicle aspiration, sperm injection, and assisted rupture (FASIAR) technique.
Design:
Prospective, observational study.
Setting:
University and health maintenance organization-based infertility centers.
Patient(S):
Infertile couples were enrolled from our professional practices. All patients were
Intervention(S):
After administration of clomiphene citrate, patients were given an intramuscular injection of hCG when the lead ovarian follicle was >16-18 mm in diameter by transvaginal ultrasonography. A modified FASIAR procedure was performed 22 to 28 hours after hCG injection.
Main Outcome Measure(S):
Clinical pregnancy rate.
Result(S):
No clinical pregnancies were observed with the modified FASIAR technique.
Conclusion(S):
The FASIAR technique is still an attractive and economical technique. Our modification of the FASIAR technique, however, resulted in a suboptimal cycle fecundity.
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