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Micropumps to support the heart during CABG.
B Meyns1, P Sergeant, T Nishida
1Department of Cardiac Surgery, Gasthuisberg University Hospital, Herestraat 49, KULeuven, 3000, Leuven, Belgium. burt.meyns@un.kuleuven
Summary
Micropump support significantly improved hemodynamic performance and myocardial blood flow during beating heart coronary artery bypass grafting (CABG) surgery for triple vessel disease in sheep.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
- Hemodynamics
Background:
- Beating heart coronary artery bypass grafting (CABG) for complex triple vessel disease presents challenges.
- Myocardial ischemia during surgical manipulation can lead to adverse outcomes.
Purpose of the Study:
- To evaluate the efficacy of biventricular micropump support during beating heart CABG.
- To assess the impact of micropumps on myocardial protection and hemodynamic stability.
Main Methods:
- 12 sheep underwent sequential occlusion of three coronary arteries.
- Animals were divided into control and biventricular micropump support groups.
- Hemodynamics and myocardial flow were assessed during occlusion and reperfusion.
Main Results:
- Micropump-supported animals showed significantly better hemodynamic performance and myocardial contractility post-procedure.
- Subendocardial blood flow was markedly improved in all left ventricular regions in the supported group.
- Survival rates were higher in the micropump-supported group compared to controls.
Conclusions:
- Biventricular micropump support enhances myocardial resistance to ischemia during beating heart CABG.
- This technology can improve the safety and applicability of CABG for complex triple vessel disease.