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Enhanced fluoride uptake by teeth through use of iontophoretic techniques
Pharmacology and Therapeutics in Dentistry
|January 1, 1975
Summary
Anodic polarization of gold electrodes in human teeth enhanced fluoride ion uptake. Subsequent cathodic polarization confirmed fluoride ion absorption by the teeth.
Area of Science:
- Biomaterials Science
- Electrochemistry
- Dental Research
Background:
- Fluoride ion uptake is crucial for dental caries prevention.
- Electrochemical methods offer potential for controlled ion delivery to teeth.
Purpose of the Study:
- To investigate the effect of electric currents on fluoride ion uptake by human teeth in vitro.
- To determine if anodic polarization enhances fluoride ion absorption.
Main Methods:
- Human teeth were subjected to electrochemical treatment with embedded gold electrodes.
- Fluoride ion concentration changes in the electrolyte were measured.
- Subsequent cathodic polarization in fluoride-free electrolyte assessed fluoride release.
Main Results:
- Anodic polarization of the gold electrode resulted in enhanced fluoride ion uptake by the teeth.
- Fluoride ions were released from the teeth during subsequent cathodic polarization, confirming uptake.
Conclusions:
- Electrochemical treatment, specifically anodic polarization, can significantly enhance fluoride ion uptake in human teeth.
- This in vitro study demonstrates a novel method for potentially improving dental fluoride delivery and retention.