[Astrocytoma in a 6-year-old girl after the treatment for acute lymphoblastic leukemia]

In recent years we observe the increasing number of event-free survivals of patients with acute lymphoblastic leukaemia. It is achieved with multidrug chemotherapy regiment. The important part of protocols is prophylaxis e.g. with radiation therapy of CNS. It is followed by drug toxicity and side effects of treatment (e.g. secondary CNS tumours). In our hospital we observed the case of 6-year-old girl with CNS tumour-astrocytoma. According to the regimen for ALL the radiation therapy of CNS was performed. Three months after neurosurgical operation the local recurrence was observed. The patient died of the progression of disease.