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Gastric Bypass after Cardiac Transplantation
1Oregon Center for Bariatric Surgery, Eugene, OR, 97401, USA.
Obesity Surgery
|May 1, 1995
Summary
Gastric bypass surgery resolved severe obesity hypoventilation syndrome, uncontrolled diabetes, and hypertension in a heart transplant patient. The patient achieved significant weight loss and maintained anti-rejection medications until his death 2.75 years post-procedure.
Area of Science:
- Bariatric Surgery
- Cardiology
- Endocrinology
Background:
- A 39-year-old male with a history of cardiac transplantation faced life-threatening obesity hypoventilation syndrome (OHS).
- He also suffered from severe, poorly controlled diabetes mellitus (DM) and hypertension (HBP), exacerbated by morbid obesity.
Purpose of the Study:
- To evaluate the impact of gastric bypass surgery on OHS, DM, and HBP in a post-cardiac transplant patient.
- To assess the safety and efficacy of bariatric surgery in maintaining immunosuppressive therapy.
Main Methods:
- A gastric bypass procedure with a 45-cm Roux-limb was performed.
- Patient's weight, OHS, DM, HBP, and immunosuppressive therapy (Cyclosporine, Imuran) were monitored post-surgery.
Main Results:
- OHS resolved completely, and diabetes became undetectable off medication.
- Hypertension was significantly reduced with good control, and maximum excess weight loss reached 95%.
- Immunosuppressive therapy was maintained without complications attributable to the gastric bypass.
Conclusions:
- Gastric bypass surgery is a viable option for managing severe obesity and associated comorbidities in select post-transplant patients.
- Bariatric surgery can improve or resolve OHS, DM, and HBP, potentially enhancing graft survival and overall patient health.