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Induction Of ovulation
Y S Nandanwar1, A A Shinde, N M Mayadeo
1Department of Obstetrics and Gynaecology, Seth G. S. Medical College, Parel, Mumbai, India.
Journal of Postgraduate Medicine
|March 29, 2000
Summary
This study compared ovulation induction drugs for infertility. Clomiphene citrate showed good response, while Ayurvedic options like leptaden offered alternatives for non-responders.
Area of Science:
- Reproductive Endocrinology
- Infertility Treatment
Background:
- Anovulation is a common cause of female infertility.
- Several ovulation-inducing medications are available, each with varying efficacy and side effect profiles.
Purpose of the Study:
- To evaluate the effectiveness of different ovulation induction drugs in patients with anovulatory infertility.
- To explore alternative treatments for patients unresponsive to conventional therapies.
Main Methods:
- Sixty-one infertile patients with anovulation were enrolled.
- Medications used included clomiphene citrate, human menopausal gonadotropin (hMG), human chorionic gonadotropin (hCG), bromergocryptine, and leptadene.
- Ovulation was monitored using serial sonography.
Main Results:
- Clomiphene citrate demonstrated a good response rate.
- Patients who did not respond to clomiphene citrate, or who experienced issues with hMG/hCG, were offered Ayurvedic treatments (Aloe compound and leptadene).
Conclusions:
- Clomiphene citrate is an effective first-line treatment for anovulatory infertility.
- Ayurvedic medications like leptadene present a viable alternative for patients with limited response or tolerance to conventional ovulation induction drugs.